{"id":133,"date":"2011-11-25T13:55:18","date_gmt":"2011-11-25T13:55:18","guid":{"rendered":"http:\/\/helpmeinvestigate.com\/health\/?p=133"},"modified":"2021-10-22T07:05:20","modified_gmt":"2021-10-22T07:05:20","slug":"researching-the-link-between-capsaicin-pepper-spray-deaths-and-stimulants","status":"publish","type":"post","link":"http:\/\/helpmeinvestigate.com\/health\/2011\/11\/25\/researching-the-link-between-capsaicin-pepper-spray-deaths-and-stimulants\/","title":{"rendered":"Can you help? Researching the link between capsaicin (pepper spray) deaths and stimulants"},"content":{"rendered":"<p>I am looking for post mortem data on deaths caused by capsaicin\u00a0(pepper spray). I intend to analyse the data for links to the involvement of stimulants (particularly\u00a0pseudoephedrine,\u00a0methamphetamine and cocaine). My\u00a0rationale\u00a0is based on\u00a0<a href=\"http:\/\/www.springerlink.com\/content\/x3p1m2471j835582\/\" target=\"_blank\">Mendelson\u00a0et al, (2009)<\/a>\u00a0as indicated in my <a href=\"http:\/\/neurobonkers.com\/?p=4305\" target=\"_blank\">blog post<\/a>\u00a0on the topic (duplicated below).<\/p>\n<p><strong><em>If you can help me find this information please use the comment box below or email me.<!--more--><\/em><\/strong><\/p>\n<p>Mank thanks!<\/p>\n<p><a href=\"http:\/\/neurobonkers.com\">Neurobonkers<\/a><\/p>\n<p>neurobonkers@gmail.com<\/p>\n<p><a href=\"http:\/\/neurobonkers.com\/?p=4305\" target=\"_blank\"><strong>Pepper spray and cocaine, a little known lethal combination<\/strong><\/a><\/p>\n<div id=\"attachment_4307\" style=\"width: 308px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/neurobonkers.com\/wp-content\/uploads\/2011\/11\/pepper-spray.jpg\"><img aria-describedby=\"caption-attachment-4307\" loading=\"lazy\" class=\"size-full wp-image-4307 \" style=\"border-style: initial; border-color: initial; text-align: center;\" src=\"http:\/\/neurobonkers.com\/wp-content\/uploads\/2011\/11\/pepper-spray.jpg\" alt=\"Pepper spray compared to natural chili pepper\" width=\"298\" height=\"420\" \/><\/a><p id=\"caption-attachment-4307\" class=\"wp-caption-text\">Pepper spray compared to natural chili pepper<\/p><\/div>\n<p>Yesterday <a href=\"http:\/\/slog.thestranger.com\/slog\/archives\/2011\/11\/21\/pregant-woman-blasted-with-pepper-spray-by-spd-reportedly-miscarries\">it emerged that a pregnant woman who had been sprayed with pepper spray at a demonstration has lost her baby<\/a>. This is a shocking claim but it isn&#8217;t surprising when you consider the toxicity of pepper spray and the fact that it is banned for use in warfare under Article I.5 of the\u00a0<a href=\"http:\/\/www.opcw.org\/about-chemical-weapons\/types-of-chemical-agent\/riot-control-agents\/\" rel=\"nofollow\" target=\"_blank\">Chemical Weapons Convention<\/a>\u00a0(signed by the US, the UK and almost <a href=\"http:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/9\/9b\/CWC_Participation.svg\/800px-CWC_Participation.svg.png\" target=\"_blank\">every other country on the planet<\/a>).Police &#8220;pepper spray&#8221; is\u00a0<a href=\"http:\/\/blogs.plos.org\/speakeasyscience\/2011\/11\/20\/about-pepper-spray\/\" target=\"_blank\">six hundred and sixty two times more powerful than\u00a0jalape\u00f1o\u00a0pepper<\/a>\u00a0and\u00a0many hundreds of times stronger than the cans available to ordinary\u00a0Americans.<\/p>\n<p>There is no debate that being sprayed with pepper spray is extremely dangerous but few know that it is known to cause\u00a0<a href=\"http:\/\/blogs.plos.org\/speakeasyscience\/2011\/11\/20\/about-pepper-spray\/\" target=\"_blank\">potentially lethal<\/a>\u00a0respiratory failure,\u00a0especially for asthma\u00a0sufferers. Most worryingly, the least informed appear to be the US police officers who are prepared to <a href=\"http:\/\/www.theatlantic.com\/politics\/archive\/2011\/11\/too-much-violence-and-pepper-spray-at-the-ows-protests\/248761\/\" target=\"_blank\">nonchalantly spray it directly in to the faces of peaceful protesters<\/a>.<\/p>\n<p>Even more worrying is the complete lack of interest by the authorities in the lethal impact that pepper spray has on individuals who have taken stimulants such as cocaine and amphetamines. The active\u00a0ingredient\u00a0in pepper spray, <a href=\"http:\/\/www.springerlink.com\/content\/x3p1m2471j835582\/\" target=\"_blank\"><strong>capsaicin\u00a0potentates\u00a0the toxicity of cocaine astronomically<\/strong>, <strong>making cocaine and pepper spray a lethal combination.<\/strong><\/a> In the two years following California&#8217;s 1992 \u00a0adoption of capsaicin based pepper spray <strong>nineteen of the twenty-six deaths caused by pepper spay also involved the use of stimulants like cocaine<\/strong> (9 involved methamphetamine, 6 cocaine, 3 methamphetamine plus cocaine, and 1 pseudoephedrine), <strong>79% of those deaths occured within one hour<\/strong>\u00a0(<a href=\"http:\/\/www.springerlink.com\/content\/x3p1m2471j835582\/\">Mendelson\u00a0et al, 2009)<\/a>. This research is supported by animal research in which capsaicin pushed mortality levels through the roof in rats administered with cocaine (<a href=\"http:\/\/www.springerlink.com\/content\/x3p1m2471j835582\/\" target=\"_blank\">Mendelson\u00a0et al, 2009<\/a>).<\/p>\n<blockquote><p>&#8220;The lethal effects of capsaicin administered with cocaine (both compounds administered intraperitoneally) were assessed in 14 groups of 20\u201340 male mice. capsaicin at 10 mg\/kg increased the lethality of cocaine in mice dosed at <strong>60 mg\/kg from 13% to 53% (<em>P<\/em>\u00a0&lt; 0.01)<\/strong> and for cocaine at <strong>75 mg\/kg from 53% to 90% (<em>P<\/em>\u00a0&lt; 0.001).<\/strong>&#8221;\u00a0(<a href=\"http:\/\/www.springerlink.com\/content\/x3p1m2471j835582\/\" target=\"_blank\">Mendelson\u00a0et al, 2009<\/a>)<\/p><\/blockquote>\n<div id=\"attachment_4308\" style=\"width: 644px\" class=\"wp-caption aligncenter\"><img aria-describedby=\"caption-attachment-4308\" loading=\"lazy\" class=\"size-full wp-image-4308\" src=\"http:\/\/neurobonkers.com\/wp-content\/uploads\/2011\/11\/pepper-spray-cop.jpg\" alt=\"\" width=\"634\" height=\"412\" \/><p id=\"caption-attachment-4308\" class=\"wp-caption-text\">Casual pepper spraying<\/p><\/div>\n<p>Footnote: If you think this is a situation that is unlikely to affect you because you aren&#8217;t the sort of person to confront a police officer you should take a look at the &#8220;crowd management&#8221; pepper spray now being developed by a subsidary of BAE and the <a href=\"http:\/\/www.theatlantic.com\/politics\/archive\/2011\/11\/too-much-violence-and-pepper-spray-at-the-ows-protests\/248761\/\" target=\"_blank\">implementation of pepper spray for crowd management already occurring\u00a0across the on US a grand scale<\/a>.<\/p>\n<div id=\"attachment_4332\" style=\"width: 610px\" class=\"wp-caption aligncenter\"><img aria-describedby=\"caption-attachment-4332\" loading=\"lazy\" class=\"size-full wp-image-4332\" src=\"http:\/\/neurobonkers.com\/wp-content\/uploads\/2011\/11\/fire-extinguisher-pepper-spray.jpg\" alt=\"fire extinguisher pepper spray\" width=\"600\" height=\"326\" \/><p id=\"caption-attachment-4332\" class=\"wp-caption-text\">If this ever gets deployed at a rave we&#39;ll have a massacre on our hands.<\/p><\/div>\n<p><strong>Reference:<\/strong><\/p>\n<p><em><span class=\"Z3988\" title=\"ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.jtitle=Forensic+Toxicology&amp;rft_id=info%3Adoi%2F10.1007%2Fs11419-009-0079-9&amp;rfr_id=info%3Asid%2Fresearchblogging.org&amp;rft.atitle=Capsaicin%2C+an+active+ingredient+in+pepper+sprays%2C+increases+the+lethality+of+cocaine&amp;rft.issn=1860-8965&amp;rft.date=2009&amp;rft.volume=28&amp;rft.issue=1&amp;rft.spage=33&amp;rft.epage=37&amp;rft.artnum=http%3A%2F%2Fwww.springerlink.com%2Findex%2F10.1007%2Fs11419-009-0079-9&amp;rft.au=Mendelson%2C+J.&amp;rft.au=Tolliver%2C+B.&amp;rft.au=Delucchi%2C+K.&amp;rft.au=Baggott%2C+M.&amp;rft.au=Flower%2C+K.&amp;rft.au=Harris%2C+C.&amp;rft.au=Galloway%2C+G.&amp;rft.au=Berger%2C+P.&amp;rfe_dat=bpr3.included=1;bpr3.tags=Biology%2CChemistry%2CMedicine%2CPsychology%2CSocial+Science%2CHealth\">Mendelson, J., Tolliver, B., Delucchi, K., Baggott, M., Flower, K., Harris, C., Galloway, G., &amp; Berger, P. (2009). Capsaicin, an active ingredient in pepper sprays, increases the lethality of cocaine Forensic Toxicology, 28 (1), 33-37 DOI: <a href=\"http:\/\/dx.doi.org\/10.1007\/s11419-009-0079-9\" rev=\"review\">10.1007\/s11419-009-0079-9<\/a><\/span><\/em><\/p>\n<div class=\"tweetthis\" style=\"text-align:left;\"><p> <a target=\"_blank\" rel=\"nofollow\" class=\"tt\" href=\"http:\/\/twitter.com\/intent\/tweet?text=Can+you+help%3F+Researching+the+link+between+capsaicin+%28pepper+spray%29+deaths+and+stimulants+http%3A%2F%2Fhelpmeinvestigate.com%2Fhealth%2F%3Fp%3D133\" title=\"Post to Twitter\"><img class=\"nothumb\" src=\"http:\/\/helpmeinvestigate.com\/health\/wp-content\/plugins\/tweet-this\/icons\/en\/twitter\/tt-twitter.png\" alt=\"Post to Twitter\" \/><\/a> <a target=\"_blank\" rel=\"nofollow\" class=\"tt\" href=\"http:\/\/twitter.com\/intent\/tweet?text=Can+you+help%3F+Researching+the+link+between+capsaicin+%28pepper+spray%29+deaths+and+stimulants+http%3A%2F%2Fhelpmeinvestigate.com%2Fhealth%2F%3Fp%3D133\" title=\"Post to Twitter\">Tweet This Post<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>I am looking for post mortem data on deaths caused by capsaicin\u00a0(pepper spray). I intend to analyse the data for links to the involvement of stimulants (particularly\u00a0pseudoephedrine,\u00a0methamphetamine and cocaine). My\u00a0rationale\u00a0is based on\u00a0Mendelson\u00a0et al, (2009)\u00a0as indicated in my blog post\u00a0on the &hellip; <a href=\"http:\/\/helpmeinvestigate.com\/health\/2011\/11\/25\/researching-the-link-between-capsaicin-pepper-spray-deaths-and-stimulants\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[15],"tags":[71,76,75,73,72,74],"_links":{"self":[{"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/posts\/133"}],"collection":[{"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/comments?post=133"}],"version-history":[{"count":6,"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/posts\/133\/revisions"}],"predecessor-version":[{"id":996,"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/posts\/133\/revisions\/996"}],"wp:attachment":[{"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/media?parent=133"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/categories?post=133"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/helpmeinvestigate.com\/health\/wp-json\/wp\/v2\/tags?post=133"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}